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17-Ketosteroids urine test

17-ketosteroids are substances that form when the body breaks down male steroid sex hormones called androgens and other hormones released by the adrenal glands in males and females, and by the testes in males.

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Urine sample

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How the Test is Performed

A 24-hour urine sample is needed. You will need to collect your urine over 24 hours. Your health care provider will tell you how to do this. Follow instructions exactly to ensure accurate results.

How to Prepare for the Test

Your provider will ask you to temporarily stop any medicines that may affect the test results. Be sure to tell your provider about all the medicines you take. These include:

DO NOT stop taking any medicine before talking to your provider.

How the Test will Feel

The test involves normal urination. There is no discomfort.

Why the Test is Performed

Your provider may order this test if you have signs of a disorder associated with abnormal levels of androgens.

Normal Results

Normal values are as follows:

Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your doctor about the meaning of your specific test results.

What Abnormal Results Mean

Increased levels of 17-ketosteroids may be due to:

Decreased levels of 17-ketosteroids may be due to:

Risks

There are no risks with this test.

Related Information

Congenital adrenal hyperplasia
Cushing syndrome
Ovarian cancer
Testicular cancer
Addison disease
Hypopituitarism

References

Bertholf RL, Cooper M, Winter WE. Adrenal cortex. In: Rifai N, ed. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 6th ed. St Louis, MO: Elsevier; 2018:chap 66.

Chernecky CC, Berger BJ. Metyrapone (cortisol) - 24-hour urine. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures. 6th ed. St Louis, MO: Elsevier Saunders; 2013:787.

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Review Date: 11/20/2017  

Reviewed By: Laura J. Martin, MD, MPH, ABIM Board Certified in Internal Medicine and Hospice and Palliative Medicine, Atlanta, GA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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