Stable factor; Proconvertin; Autoprothrombin I
The factor VII assay is a blood test to measure the activity of factor VII. This is one of the proteins in the body that helps the blood clot.
A blood sample is needed.
You may need to temporarily stop taking some medicines before this test. Your health care provider will tell you which ones.
When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or slight bruising. This soon goes away.
This test is used to find the cause of abnormal bleeding (decreased blood clotting). This decreased clotting may be caused by an abnormally low level of factor VII.
The normal value is 50% to 200% of the laboratory control or reference value.
Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different samples. Talk to your provider about the meaning of your specific test results.
Decreased factor VII activity may be related to:
There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another, and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight, but may include:
This test is most often done on people who have bleeding problems. The risk of excessive bleeding is slightly greater than for people without bleeding problems.
Chernecky CC, Berger BJ. Factor VII (stable factor, proconvertin, autoprothrombin I) - blood. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures. 6th ed. St Louis, MO: Elsevier Saunders; 2013:503-504.
Pai M. Laboratory evaluation of hemostatic and thrombotic disorders. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2018:chap 129.BACK TO TOP
Review Date: 1/29/2019
Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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