Site Map

Estradiol blood test

E2 test

An estradiol test measures the amount of a hormone called estradiol in the blood. Estradiol is one of the main types of estrogens.

I Would Like to Learn About:

How the Test is Performed

A blood sample is needed.

How to Prepare for the Test

Your health care provider may tell you to temporarily stop taking certain medicines that may affect test results. Be sure to tell your provider about all the medicines you take. These include:

DO NOT stop taking any medicine before talking to your doctor.

How the Test will Feel

When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away.

Why the Test is Performed

In women, most estradiol is released from the ovaries and adrenal glands. It is also released by the placenta during pregnancy. Estradiol is also produced in other body tissues, such as skin, fat, cells bone, brain, and liver. Estradiol plays a role in:

In men, a small amount of estradiol is mainly released by the testes. Estradiol helps prevent sperm from dying too early.

This test may be ordered to check:

The test may also be ordered to check if:

The test may also be used to monitor people with hypopituitarism and women on certain fertility treatments.

Normal Results

The results may vary, depending on the person's gender and age.

Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your doctor about the meaning of your specific test result.

What Abnormal Results Mean

Disorders that are associated with abnormal estradiol results include:

Risks

Veins and arteries vary in size from one person to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.

Other risks associated with having blood drawn are slight, but may include:

Related Information

Ovarian cancer
Vagina
Turner syndrome
Hypopituitarism

References

Carmina E, Stanczyk FZ, Lobo RA. Laboratory assessment. In: Strauss JF, Barbieri RL, eds. Yen and Jaffe's Reproductive Endocrinology. 7th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 34.

Chernecky CC, Berger BJ. Estradiol - serum. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures. 6th ed. St Louis, MO: Elsevier Saunders; 2013:488.

BACK TO TOP

Review Date: 7/17/2017  

Reviewed By: Cynthia D. White, MD, Fellow American College of Obstetricians and Gynecologists, Group Health Cooperative, Bellevue, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

ADAM Quality Logo

A.D.A.M., Inc. is accredited by URAC, for Health Content Provider (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics. This site complies with the HONcode standard for trustworthy health information: verify here.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2019 A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

A.D.A.M. content is best viewed in IE9 or above, Firefox and Google Chrome browser.