An estradiol test measures the amount of a hormone called estradiol in the blood. Estradiol is one of the main types of estrogens.
Your health care provider may tell you to temporarily stop taking certain medicines that may affect test results. Be sure to tell your provider about all the medicines you take. These include:
DO NOT stop taking any medicine before talking to your doctor.
When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away.
In women, most estradiol is released from the ovaries and adrenal glands. It is also released by the placenta during pregnancy. Estradiol is also produced in other body tissues, such as skin, fat, cells bone, brain, and liver. Estradiol plays a role in:
In men, a small amount of estradiol is mainly released by the testes. Estradiol helps prevent sperm from dying too early.
This test may be ordered to check:
The test may also be ordered to check if:
The test may also be used to monitor people with hypopituitarism and women on certain fertility treatments.
The results may vary, depending on the person's gender and age.
Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your doctor about the meaning of your specific test result.
Disorders that are associated with abnormal estradiol results include:
Veins and arteries vary in size from one person to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight, but may include:
Carmina E, Stanczyk FZ, Lobo RA. Laboratory assessment. In: Strauss JF, Barbieri RL, eds. Yen and Jaffe's Reproductive Endocrinology. 7th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 34.
Chernecky CC, Berger BJ. Estradiol - serum. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures. 6th ed. St Louis, MO: Elsevier Saunders; 2013:488.BACK TO TOP
Review Date: 7/17/2017
Reviewed By: Cynthia D. White, MD, Fellow American College of Obstetricians and Gynecologists, Group Health Cooperative, Bellevue, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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