Skip to Content

Get Vaccinated/Tested

Lee Health is now vaccinating anyone age 5+. Click here for scheduling options. Click here for a list of COVID testing sites in our community.

Default Alt Text for the banner
If this is a medical emergency, please call 911. For minor injuries and illnesses, please see one of our Lee Convenient Care locations.



Clinical Interests:

Sickle cell disease
Solid tumors
Adolescent cancer
Young adult cancer

Languages Spoken:


Patients Treated:

Young Adults


April DePombo, D.O. is a pediatric hematologist and oncologist.

Meet the Doctor

Hello. My name is April Depombo. I'm a pediatric hematologist oncologist. I treat children, adolescents, and young adults with blood disorders and cancer. I'm originally from Kansas City. I'm a big Royals fan, and I graduated twice from the University of Kansas. So, I'm definitely a Jayhawk at heart. The people really made the difference for me and influenced me the most. I've talked to different doctors and nurses, medical assistants. Everybody said, "Oh, I've been here 10 years. I've been here 20 years, 18 years." And that spoke volumes to me. Also, the fact that the team puts the focus on putting the patient first above all else, doing what's right for them. That's another thing that drew me here. I'm married and we have an 18-month-old son. So, we love to do things with him and go to the beach, go swimming, new restaurants, really exploring the new area and really making this our home.

Education & Training

Medical School:

Lincoln Memorial University DeBusk College of Osteopathic Medicine, Harrogate, TN


Miami Children’s Hospital, Miami, FL


MD Anderson Cancer Center, Houston, TX

Board Certification(s):

Pediatric Hematology-Oncology, Pediatrics