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image of Michael DeFrain, MD
image of Michael DeFrain, MD

Michael DeFrain, MD

4.9 out of 5 stars

Doctor Video



Clinical Interests:

Robotic lung surgery
Minimally invasive heart and lung surgery
Mitral valve repair and replacement
Aortic valve replacement
Atrial fibrillation surgery
Transcatheter aortic valve replacement
Coronary artery bypass

Languages Spoken:


Patients Treated:



My professional focus is on you.  As your surgeon, my goal is to guide you through treatment and return you to your family safely with your best possible quantity and quality of life.  We will achieve this goal together by reviewing your diagnostic tests, discussing your condition, and then matching the best treatment option to your particular need.  As my patient, I am motivated to provide you the safest, least invasive and most effective heart and lung surgical treatments available anywhere.  With over twenty years of learning in cardiothoracic surgery, I have become proficient at robotic pulmonary lobectomy, robotic coronary artery revascularization, minimally invasive right chest valvular heart surgery, and catheter-based treatments such as TAVR and TEVAR.  I have committed myself to these procedures because I have learned their value in improving your outcome by conveying the least possible physical impact to your body. 

Although I remain the leader, I believe in the power of the team over that of the one.  Therefore, I have helped develop, and am part of, expert teams at Health Park Hospital.  These teams are comprised of doctors, nurses, and other allied support members in cardiology, pulmonology, intensive care, anesthesia, hematology/oncology, rehabilitation and many others that are designed to ensure your safety and enable your best possible treatment outcome.  The focus is always on you, and the goal is to return you healthy and safe back to your family and your life.

●             ●             ●

Dr. DeFrain was raised the youngest of five children in East Lansing, Michigan.  He earned his undergraduate degree at the University of Michigan in Ann Arbor in 1994 and graduated from Wayne State Medical School in Detroit, Michigan in 1998.  He completed general surgery training through Michigan State University in Grand Rapids in 2003, and his cardiovascular and thoracic surgery residency through the University of Texas at the Texas Heart Institute and MD Anderson Cancer Center in Houston, Texas in 2005.  He and his wife Stephanie have four children.

Dr. DeFrain is board certified by both the American Board of Surgery and the American Board of Thoracic Surgery.  He is a fellow of the American College of Surgeons and is a member of the Denton A. Cooley Cardiovascular Surgical Society, the Southern Thoracic Surgical Association, and the Society of Thoracic Surgeons.

For the past two years, Palm Beach Media Group has recognized Dr. DeFrain as one of Southwest Florida’s top doctors from Lee Physician Group.

Dr. DeFrain’s achievements reflect the high level of care LPG providers offer every day at Lee Health, your community-owned health system. It’s the excellence you expect from providers that live, work, and care for patients right here at home.

Lee Physician Group Top Doctors

Meet the Doctor

Education & Training

Medical School:

Wayne State University School of Medicine in Detroit, Mich.


General Surgery Residency, Michigan State University in Grand Rapids, Mich.

Cardiothoracic Surgery Residency, Texas Heart Institute and MD Anderson Cancer Center, Houston, Texas

Board Certification(s):

General Surgery, Thoracic Surgery

Patient Reviews

The following ratings and reviews are based on verified feedback collected from independently administered patient experience surveys. The ratings and comments submitted by patients reflect their own views and opinions.

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  • 4.9out of 5 stars

    Explained Things Clearly

  • 4.9out of 5 stars

    Involved in Care Decisions

  • 4.9out of 5 stars

    Spent Enough Time

  • 4.9out of 5 stars

    Listened Carefully

  • 5.0out of 5 stars

    Showed Courtesy & Respect

  • 4.9out of 5 stars

    Likelihood to Recommend

4.9 out of 5 (150 ratings, 90 comments)

  • May 28, 2024

    Dr. DeFrain is always professional and courteous. He explains things well and inspires confidence. The entire staff at the office are friendly and professional.

  • May 24, 2024

    Everyone in the office was top notch

  • May 20, 2024

    Dr Defrain was very thorough during my appointment. He took the time to explain my diagnosis and the possible interventions moving forward.

  • May 18, 2024

    Dr.DuFrain Was able to transfer his medical knowledge to me in understandable, practical, real world scenarios. My wife and I feel comfortable and confident that we have the best medical person to handle my situation. We trust him.

  • May 18, 2024

    I absolutely love Dr. Defrain. He is so real and down to earth. He's very understanding and compassionate. He didn't seem rushed at all and spent time with me to reassure and comfort me.

  • May 18, 2024

    The whole staff, including the doctor were remarkable. Thank you.

  • May 13, 2024

    Dr De Frain

  • May 11, 2024

    Everyone in the office was fantastic from beginning to the end of my consultation

  • May 8, 2024

    Dr. Michael DeFrain

  • May 4, 2024

    All staff was excellent, all deserve the very best! Thank you!

  • May 3, 2024

    Dr Defrain talked to us not over us. He knew we were scared and he explained things and calmed us dow. Thanks to the entire team for their knowledge and support.

  • May 3, 2024

    Erin the receptionist in Dr DeFrain's office really made me feel welcome and was very helpful in explaining something to me The. PA I forgot her name was very knowledgeable and explained some things to me that related to my valve. Dr DeFrain explain to everyth ing to my son and I and gave us different options on how to proceed. In the TEE surgical unit. The staff was absolutely fantastic. They explained everything to me before the procedure it was very attentive to anything that I needed. I'd like to thank Gina and Roy. I did not get the names of everyone that performed the TEE except for doctor Towe and would also like to thank them for making me comfortable. I would recommend this hospital since they really go out of their way to make your stay there pleasant

  • Apr 29, 2024

    From initial intake at the reception desk through all the process, everyone was extremely professional and also friendly and welcoming. Dr. Defrain apologized for being delayed, something that rarely occurs (the apology, not the delay), but I felt that were I being treated and it caused a delay, I would get the best care. I understand doctors can be delayed by unexpected circumstances.

  • Apr 26, 2024

    Not one really but rather every person exceeded any/all expectations. Speaking as a retired medical professional my experience was refreshing, informative, professional and personal. Thank you!

  • Apr 26, 2024

    Excellent to outstanding. They listen to everything I had to say.. they answered all my questions in detail and they are very professional..

  • Apr 16, 2024

    Doctor Defrain.

  • Apr 12, 2024

    Carmen is always helpful an cheery. She always explains what's going on.

  • Apr 2, 2024

    Dr. DeFrain

  • Apr 2, 2024

    Very positive and assuring

  • Apr 1, 2024

    I was very impressed with Dr DeFrain and staff

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