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image of Michael DeFrain, MD
image of Michael DeFrain, MD

Michael DeFrain, MD

4.8 out of 5 stars

Doctor Video



Clinical Interests:

Robotic lung surgery
Minimally invasive heart and lung surgery
Mitral valve repair and replacement
Aortic valve replacement
Atrial fibrillation surgery
Transcatheter aortic valve replacement
Coronary artery bypass

Languages Spoken:


Patients Treated:



My professional focus is on you.  As your surgeon, my goal is to guide you through treatment and return you to your family safely with your best possible quantity and quality of life.  We will achieve this goal together by reviewing your diagnostic tests, discussing your condition, and then matching the best treatment option to your particular need.  As my patient, I am motivated to provide you the safest, least invasive and most effective heart and lung surgical treatments available anywhere.  With over twenty years of learning in cardiothoracic surgery, I have become proficient at robotic pulmonary lobectomy, robotic coronary artery revascularization, minimally invasive right chest valvular heart surgery, and catheter-based treatments such as TAVR and TEVAR.  I have committed myself to these procedures because I have learned their value in improving your outcome by conveying the least possible physical impact to your body. 

Although I remain the leader, I believe in the power of the team over that of the one.  Therefore, I have helped develop, and am part of, expert teams at Health Park Hospital.  These teams are comprised of doctors, nurses, and other allied support members in cardiology, pulmonology, intensive care, anesthesia, hematology/oncology, rehabilitation and many others that are designed to ensure your safety and enable your best possible treatment outcome.  The focus is always on you, and the goal is to return you healthy and safe back to your family and your life.

●             ●             ●

Dr. DeFrain was raised the youngest of five children in East Lansing, Michigan.  He earned his undergraduate degree at the University of Michigan in Ann Arbor in 1994 and graduated from Wayne State Medical School in Detroit, Michigan in 1998.  He completed general surgery training through Michigan State University in Grand Rapids in 2003, and his cardiovascular and thoracic surgery residency through the University of Texas at the Texas Heart Institute and MD Anderson Cancer Center in Houston, Texas in 2005.  He and his wife Stephanie have four children.

Dr. DeFrain is board certified by both the American Board of Surgery and the American Board of Thoracic Surgery.  He is a fellow of the American College of Surgeons and is a member of the Denton A. Cooley Cardiovascular Surgical Society, the Southern Thoracic Surgical Association, and the Society of Thoracic Surgeons.

In 2023, Palm Beach Media Group recognized Dr. DeFrain as one of Southwest Florida’s top doctors from Lee Physician Group.

Dr. DeFrain’s achievements reflect the high level of care LPG providers offer every day at Lee Health, your community-owned health system. It’s the excellence you expect from providers that live, work, and care for patients right here at home.

Lee Physician Group Top Doctors

Meet the Doctor

Education & Training

Medical School:

Wayne State University School of Medicine in Detroit, Mich.


General Surgery Residency, Michigan State University in Grand Rapids, Mich.

Cardiothoracic Surgery Residency, Texas Heart Institute and MD Anderson Cancer Center, Houston, Texas

Board Certification(s):

General Surgery, Thoracic Surgery

Patient Reviews

The following ratings and reviews are based on verified feedback collected from independently administered patient experience surveys. The ratings and comments submitted by patients reflect their own views and opinions.

Please see our FAQ page for more information.

  • 4.2out of 5 stars

    Quality of Care

  • 4.8out of 5 stars

    Explained Things Clearly

  • 4.8out of 5 stars

    Involved in Care Decisions

  • 4.8out of 5 stars

    Spent Enough Time

  • 4.8out of 5 stars

    Listened Carefully

  • 4.9out of 5 stars

    Showed Courtesy & Respect

  • 4.8out of 5 stars

    Likelihood to Recommend

4.8 out of 5 (113 ratings, 63 comments)

  • May 12, 2023

    Doreen [ ]was great. Dr. DeFrain was awesome and his nursing staff was phenomenal!

  • May 6, 2023

    really like the doctor

  • Apr 28, 2023

    Maybe the best Dr. I've ever had.

  • Apr 28, 2023

    Dr Defrain, his nurse practitioner, and the front desk staff. I would recommend them highly.

  • Apr 24, 2023

    Never met a more friendly staff

  • Apr 11, 2023

    Everyone was very responsive and courteous and went above to make things much easier

  • Apr 10, 2023

    Tyler, Erica, Carmen all where very helpful and knowledgeable at what they did. I was very impressed with scheduling, getting medical from another clinic, on time. I'm seasonal patient and thought I got excellent care. I'm planning on getting my treatment and surgery done here.

  • Apr 8, 2023

    Their true concern and willingness to understand and address our concerns.

  • Apr 8, 2023

    Everything was outstanding!

  • Apr 7, 2023

    The whole staff was great

  • Apr 3, 2023

    I am impressed with the caring of all the staff and the doctor the news of my surgery. He was so professional and yet gave me what facts we had on hand and what to expect through it all. I feel he is who our God chose to make me well and I have confidence in h is decisions. Thank you.

  • Mar 31, 2023

    Everyone we encountered was very conscientious, helpful, and friendly.

  • Mar 24, 2023

    Dr. DeFrain

  • Mar 24, 2023

    The moment I step in the doctors office all the person were so welcoming to me

  • Mar 14, 2023

    Don't recall specific names but everyone was courteous and professional.

  • Mar 6, 2023

    My wife was with me for my appointment. We both came away feeling that Dr. DeFrain answered all our questions and we came away with a better understanding of my options and will help us in our decision making process.

  • Feb 17, 2023

    They were all outstanding!

  • Feb 4, 2023

    My whole experience was awesome

  • Jan 21, 2023

    The whole team.was excellent and worked well together.

  • Jan 16, 2023

    Dr Defrain was the best doctor I have ever seen, I have had 48 doctors and 3 dentists. You are so lucky to have him. I was blessed to get him as mine

Verified Ratings and Reviews Powered by Ratings.MD